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The ingredient, not the marketing
Most saffron supplements are not the saffron that was studied.
Affron® is the standardised extract used in most published human trials on saffron for mood. Here is the difference, and why the dose on the label matters more than the name on the front.
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$1.75 per serving, as low as $1.40 on subscription. 20 stick packs per order. Free shipping over $50.
What Affron® actually is
Affron is a patented saffron extract standardised to consistent levels of its two active compounds, crocins and safranal.
Culinary saffron is not standardised. Its active content varies batch to batch, which is why it is not what researchers use. Affron guarantees a consistent level of those actives in every batch, and it is manufactured by Pharmactive Biotech.
The dose is the whole argument
The dose used in most positive clinical trials is 28 to 30mg per day of a standardised extract.
Mood Mod provides 30mg per serving, a deliberate margin above the 28mg studied dose so every stick delivers at least the full clinical amount even after normal manufacturing variation. A product that lists saffron but not the extract or the dose is telling you very little.
Affron® Saffron30mg
L-Theanine200mg
Magnesium Glycinate100mg
B6 + B122.5mg · 25mcg
Landmark clinical trial, 2025
The largest Affron trial to date, published in The Journal of Nutrition in 2025, enrolled 202 adults with subclinical depressive symptoms. Participants taking 28mg of Affron daily for 12 weeks showed significantly greater improvement in mood compared to the placebo group, and reported reduced daily feelings of sadness and stress as early as five weeks into the study.
72%Achieved clinically meaningful improvement
202Adults enrolled
5 wksTo noticeable reduction in stress
How it works, briefly
Crocins support the reuptake of dopamine and norepinephrine, while safranal primarily influences serotonin activity.
Because saffron acts on serotonin pathways, anyone taking an SSRI or other serotonergic medication should speak with their doctor before use.
See the full breakdown
$1.75 per serving, as low as $1.40 on subscription. 20 stick packs per order. Free shipping over $50.
✓ Clinically Studied
✓ cGMP Certified
✓ 3rd Party Tested
✓ Vegan
✓ Sugar Free
✓ Non-GMO
✓ Gluten Free
✓ Soy Free
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. If you are pregnant, breastfeeding, or taking an SSRI or other serotonergic medication, speak with your doctor before use.
Where to start
Pick your supply
The trials ran four to eight weeks, so 40 days is where we point people.
Buying once. 2 bags save 5% and 3 bags save 10% automatically at checkout.
Get 40 days30-day money-back guarantee · free shipping over $50
30DAY
30-day money-back guarantee
Try it for 30 days. If it is not for you, contact us within 30 days of delivery and we will refund your first order in full. Opened or unopened. If we send the wrong thing or it arrives damaged, we pay the return
shipping.
Before you decide
How long before I notice anything?
Longer than you want. The trials ran four to eight weeks and that is the window to judge it on. If you are looking for something that works this afternoon, this is not it.
Can I take it with what I already take?
It is a drink mix, not a replacement for anything. That said, if you take prescription medication, are pregnant or nursing, talk to your doctor before starting this or any supplement.
Am I locked into a subscription?
No. Untick the subscribe box above to buy once. If you do subscribe, you can pause, skip, change the size or cancel at any time, including before a second order ships.
What is actually in it?
Per stick: 30mg affron® saffron extract, 200mg L-theanine, 100mg magnesium glycinate, plus B vitamins and electrolytes. Sugar free, caffeine free, orange cream.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Consult a physician before use, particularly if you are pregnant, nursing, or taking medication.
40 days · $59.42$1.48 a day
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